Fig. 2
From: Flaxseed oil as a protective agent against bisphenol-A deleterious effects in male mice
a Testis of control mice showing normal spermatogenesis within the seminiferous tubules (ST). b Testis of BPA-treated mice showing severe necrosis and loss of the spermatogonial layers with multiple spermtide giant cells formation (arrow) in most of the seminiferous tubules. c Testis of BPA-treated mice showing congestion of the interstitial blood vessel, destructed and abnormal spermatid formation (thin arrow), spermatid giant cells (thick arrow), and loss of most of the spermatogonial cell layers. d Testis of FXO-treated mice before BPA treatment showing a moderate degree of preservation of a large number of the spermatogonial cells (arrow) and mild interstitial edema (E). e Testis of FXO-treated mice concurrently with BPA showing marked defective spermatogenesis and presence of extensive debris (arrow) in the lumen of the seminiferous tubules. f Testis of FXO-treated mice after BPA treatment showing congested blood vessels (C) nuclear pyknosis (P) and destruction of many spermatogonial cells with slightly active spermatogenesis in scanty seminiferous tubules (arrow). (H&E, × 400)