Structural basis to identify a target site in Shiga toxin for the inhibitor discovery against growth of Shiga toxin-producing E. coli

Bulletin of the National Research Centre

Table 2 Physiochemical attributes of TVP

Property	Value
Number of amino acids	10 (Tiny = 2, Small = 5, Aliphatic = 2, Polar = 2, non-polar = 6, charged = 4, Basic = 4)
Atomic composition	Carbon: 50 Hydrogen:90 Nitrogen:22 Oxygen:11 Sulfur:01
Total number of negatively charged residues (Asp + Glu)	0
Total number of positively charged residues (Arg + Lys)	4
Formula	C₅₀H₉₀N₂₂O₁₁S₁
Extinction coefficients	0 (will not be visible by UV spectrophotometry)
Estimated half-life	> 30 h (mammalian reticulocytes, in vitro and > 10 h (Escherichia coli, in vivo)
Instability index	243.42
Aliphatic index	20
Grand average of hydropathicity (GRAVY) value	− 1.730