Fig. 1From: One health initiative to mitigate the challenge of antimicrobial resistance in the perspectives of developing countriesMolecular mechanism of antimicrobial resistance. The diagram shows that enzymatic inactivation of antimicrobials (antibiotic alteration), alteration of a drug target (target bypass), decreased outer membrane permeability (decreased uptake), and active drug efflux (efflux pump) are the four basic mechanisms of AMRBack to article page