Evaluation | Results | Conclusions |
---|---|---|
Elementi + | Probiotics are given in the form of tablets 2 times a day and contain L. reuteri (Ausenda et al. 2023) | It is necessary to know which form of administration of probiotics is most effective (Ausenda et al. 2023) |
Oral application of probiotics in any type of administration is effective (Mishra et al. 2021) | Antimicrobial effects of probiotics need to be further investigated (Mishra et al. 2021) | |
Reduction after 6 months of use in gel form of probiotics (Donos et al. 2020) | The long-term effect of probiotics and the modulatory host effect should be seen (Donos et al. 2020) | |
Probiotics add to the positive effect of periodontitis treatment with non-surgical periodontal therapy (Minić et al. 2022) | The positive effect of probiotics is observed after 1 month of application (Minić et al. 2022) | |
L.reuteri has a positive effect against P.gingivalis, even if it is taken in the form of tablets (Galofré et al. 2018) | L. reuteri should be applied as a tablet once a day for 30 days. Its effect on peri-implantitis should be checked (Galofré et al. 2018) | |
The effects of probiotics as an oral cavity rinse are clearly observed after 1 month and after 3 months of application (Ghasemi et al. 2020) | Probiotics are effective even if they are used as rinses of the oral cavity (Ghasemi et al. 2020) | |
Element + / − | It only reduces the depth of the pockets by 4-6 mm (Vives-Soler and Chimenos-Küstner 2020) | Accurate application protocols are needed (Vives-Soler and Chimenos-Küstner 2020) |
Giving probiotics twice a day for 3 months has the same effects as giving systemic antibiotics for 7 days (Ikram et al. 2019) | L.reuteri is the probiotic as effective as antibiotics for the treatment of chronic periodontitis (Ikram et al. 2019) | |
The application of the probiotic containing L. reuteri is effective for reducing pockets proven after 21 days and after 3 months of application (Song and Liu 2020) | The healing effect of the probiotic is short term (Song and Liu 2020) | |
Application of L. reuteri reduces the depth of pockets when applied 2 tablets per day for 21 consecutive days (Theodoro et al. 2019) | Probiotics do not reduce the depth of moderate or severe deep pockets (Theodoro et al. 2019) | |
Application of probiotics reduces the depth of pockets (20) | The reduction of pocket depth by probiotics is the same as with the application of chlorhexidine in Curasept Periodontal Gel (Butera et al. 2022) | |
Element − | The depth of the pockets varies in the same way as in the case of applying only gingival curettage (Patyna et al. 2021) | Further studies are needed to determine the added effects of probiotic treatment (Patyna et al. 2021) |
There is no difference in the reduction of pocket depth even after 3 months if we use Bifidobacterium animalis (Özener et al. 2023) | The administration of probiotics has shown limited clinical and microbiological effects in the treatment of patients with periodontitis (Özener et al. 2023) | |
Probiotics can be used as host modulators, but the results are the same as applying other medicinal healing formulas (Corbella et al. 2021) | So far, there are conflicting data on the effect of probiotics for the treatment of chronic periodontitis (Corbella et al. 2021) | |
L. reuteri with the application in the form of tablets 2 times a day for 28 days did not bring increased clinical efficacy compared to non-periodontal surgical therapy (Pelekos et al. 2019) | There are no statistically significant intergroup differences in the advantages recorded at different time points (Pelekos et al. 2019) |