Exploration of tumor growth regression of quinoa and chia oil nanocapsules via the control of PIK3CA and MYC expression, anti-inflammation and cell proliferation inhibition, and their hepatorenal safety in rat breast cancer model

Bulletin of the National Research Centre

Table 4 Effect of chia and quinoa oil nanocapsules on liver functions

	Control	Corn oil	Chia NC 100 mg/kg	Quinoa NC 100 mg/kg	Chia NC 200 mg/kg	Quinoa NC 200 mg/kg	Breast tumor	Breast tumor + 5-Flu	Breast tumor + Chia NC 100 mg/kg	Breast tumor + Quinoa NC 100 mg/kg	Breast tumor + Chia NC 200 mg/kg	Breast tumor + Quinoa NC 200 mg/kg
ALT	47.25 + 2.36d	51.48 + 0.48bc	52.68 + 1.06c	36.21 + 2.47d	54.48 + 0.56bc	36.23 + 3.28d	60.88 + 1.83a	52.59 + 1.13bc	58.32 + 1.71ab	52.16 + 1.92bc	55.42 + 2.57bc	55.05 + 1.22b
AST	120.82 + 12.03a	106.17 + 2.35 cd	106.55 + 2.46 cd	107.21 + 2.51bc	104.66 + 2.16 cd	100.55 + 3.30c	115.25 + 3.03ab	103.18 + 3.53c	112.06 + 1.62bc	113.75 + 1.74ab	105.53 + 3.17 cd	112.94 + 5.10ab
ALP	72.31 + 2.46d	52.72 + 1.66e	121.38 + 3.63bc	131.71 + 2.26b	131.83 + 5.13b	95.67 + 2.16c	174.45 + 7.80a	115.98 + 9.07bc	124.64 + 3.95bc	168.11 + 2.74a	111.38 + 4.41c	160.88 + 17.03a

Data are expressed as mean ± SE (n = 6). Groups with unlike superscript letters in each raw were significantly different P ≤ 0.05)