Skip to main content

Table 2 Correlation of clinicopathological features of colorectal carcinoma patients with MSI status patterns

From: Microsatellite instability screening in colorectal carcinoma: immunohistochemical analysis of MMR proteins in correlation with clinicopathological features and Ki-67 protein expression

Clinicopathological features (no. of cases)

MSI-H (14)

MSI-L (10)

MSS (26)

P-value

Gender

Male (20)

6

4

10

0.789 (NS)

Female (30)

8

6

16

Age (yrs)

 < 50 (18)

4

2

12

0.208 (NS)

 ≥ 50 (32)

10

8

14

Tumor size

 < 5 cm (14)

0

4

10

0.015 (S)

 ≥ 5 cm (36)

14

6

16

Tumor site

Right (16)

2

6

8

0.186 (NS)

Left (20)

8

2

10

Rectum (14)

4

2

8

Tumor grade

II (30)

10

8

12

0.05 (S)

III (20)

4

2

14

T-classification

T1 (4)

2

0

2

0.0162 (S)

T2 (8)

2

4

2

T3 (24)

6

6

12

T4 (14)

4

0

10

N-classification

N0 (22)

6

6

10

0.295 (NS)

N1 (18)

6

4

8

N2 (10)

2

0

8

M-classification

M0 (44)

12

10

22

0.777 (NS)

M1 (6)

2

0

4

Stage

I (4)

2

2

0

0.0391 (S)

II (18)

4

4

10

III (24)

6

4

14

IV (4)

2

0

2

Duke’s classification*

A (6)

2

0

4

0.365 (NS)

B (16)

4

6

6

C (24)

6

4

14

D (4)

2

0

2

  1. *Dukes stage A bowel cancer: the cancer is only in the inner lining of the bowel. Dukes stage B bowel cancer: the cancer has invaded the muscle. Dukes stage C bowel cancer: the cancer has invaded the nearby lymph nodes. Dukes stage D bowel cancer: the cancer has metastasized