Bulletin of the National Research Centre

Table 5 Tl(I) content in various organs of the rat after 28 days dosing interval

From: Toxicity and antidotal treatment by synthesized and optimized ferric(III) hexacyanoferrate(II) for thallium

Tissue	Tl(I) content (µg/g)
	Positive control Tl(I)	PB-1	PB-2	Radiogardase®-Cs
Liver	0.220 ± 0.011	0.127 ± 0.009^a***	0.116 ± 0.006^a***	0.068 ± 0.009^a***
Kidney	1.230 ± 0.089	0.282 ± 0.064^a***	0.488 ± 0.064^a**	0.046 ± 0.016^***
Heart	0.464 ± 0.029	0.434 ± 0.045	0.564 ± 0.018	0.386 ± 0.038
Stomach	0.237 ± 0.04	0.104 ± 0.007^a*	0.108 ± 0.023^b*	0.054 ± 0.025^**
Bone	0.220 ± 0.012	0.103 ± 0.021^a***	0.179 ± 0.035^a***	0.074 ± 0.026^a***
Colon	0.453 ± 0.016	0.144 ± 0.028^a***	0.154 ± 0.016^a***	0.047 ± 0.016^a***
Intestine	0.545 ± 0.038	0.247 ± 0.031^a***	0.392 ± 0.040^a***	0.226 ± 0.011^a***
Brain	0.282 ± 0.024	0.215 ± 0.011^a***	0.212 ± 0.019^a***	0.126 ± 0.011^a***
Muscles	0.370 ± 0.094	0.105 ± 0.003^a*	0.141 ± 0.022^a*	0.051 ± 0.003^**
Spleen	1.060 ± 0.055	0.288 ± 0.041^a***	0.379 ± 0.037^a***	0.114 ± 0.004^a***
Adrenal gland	21.900 ± 1.960	14.400 ± 0.898^a**	15.500 ± 1.141^ba*	8.460 ± 0.131^a***
Whole body retention	26.980 ± 2.243	16.234 ± 1.153	18.233 ± 1.584	9.628 ± 0.314

^aControl group
Values are presented as Mean ± SEM. (N = 5) after 28 days of treatment. Significance is shown as ^***p < 0.001, ^**p < 0.01, ^*p < 0.05 compared to positive control group (Tl(I))

Back to article page