Table 2 Effect on biochemical parameters during sub-acute toxicity study of PB -1 and PB -2
Biochemical parameters | Male | Female | ||||
|---|---|---|---|---|---|---|
Control | PB -1 | PB-2 | Control | PB-1 | PB-2 | |
Liver function test | ||||||
Alkaline phosphatase (ALP) (U/L) | 95.100 ± 3.580 | 95.040 ± 3.205 | 95.010 ± 2.025 | 94.840 ± 2.196 | 94.040 ± 1.992 | 94.780 ± 1.296 |
Aspartate transaminase (AST) (U/L) | 152.900 ± 2.738 | 153.200 ± 2.723 | 153.200 ± 2.232 | 153.300 ± 2.912 | 152.900 ± 1.467 | 152.7 ± 2.135 |
Alanine transaminase (ALT) (U/L) | 61.930 ± 1.985 | 62.580 ± 1.394 | 62.630 ± 1.264 | 62.420 ± 1.055 | 62.560 ± 0.932 | 62.640 ± 1.215 |
Globulin (g/dL) | 3.400 ± 0.397 | 3.380 ± 0.3564 | 3.380 ± 0.3564 | 3.350 ± 0.284 | 3.470 ± 0.318 | 3.470 ± 0.318 |
Albumin (g/dL) | 3.608 ± 0.269 | 3.600 ± 0.158 | 3.610 ± 0.1653 | 3.680 ± 0.254 | 3.770 ± 0.226 | 3.730 ± 0.208 |
Cholesterol (mg /dL) | 70.603 ± 4.963 | 70.420 ± 3.563 | 70.360 ± 2.791 | 68.490 ± 7.100 | 69.890 ± 3.170 | 69.790 ± 2.204 |
Total Protein (g/dL) | 6.540 ± 0.209 | 6.560 ± 0.241 | 6.560 ± 0.241 | 6.522 ± 0.259 | 6.576 ± 0.278 | 6.558 ± 0.151 |
Kidney function test | ||||||
Calcium (mg/dL) | 8.520 ± 0.345 | 8.600 ± 0.245 | 8.596 ± 0.2356 | 8.790 ± 0.2498 | 8.830 ± 0.141 | 8.810 ± 0.079 |
Phosphorus (mg/dL) | 5.740 ± 0.3058 | 5.620 ± 0.192 | 5.646 ± 0.233 | 6.070 ± 0.3878 | 6.012 ± 0.162 | 6.112 ± 0.318 |
Uric acid (mg/dL) | 4.340 ± 0.289 | 4.340 ± 0.2074 | 4.348 ± 0.234 | 4.620 ± 0.2599 | 4.786 ± 0.217 | 4.770 ± 0.155 |
BUN (mg/dL) | 12.430 ± 0.351 | 12.440 ± 0.355 | 12.500 ± 0.145 | 12.470 ± 0.2411 | 12.480 ± 0.304 | 12.470 ± 0.340 |
Blood urea (mg/dL) | 26.930 ± 0.035 | 26.260 ± 0.654 | 26.330 ± 0.352 | 26.58 ± 0.314 | 26.420 ± 0.248 | 26.440 ± 0.294 |
Creatinine (mg/dL) | 0.780 ± 0.045 | 0.760 ± 0.055 | 0.7720 ± 0.0303 | 0.77 ± 0.033 | 0.790 ± 0.029 | 0.780 ± 0.026 |
Electrolytes | ||||||
Chloride (mmol/L) | 102.300 ± 1.838 | 101.900 ± 1.301 | 101.800 ± 1.421 | 103.700 ± 1.365 | 103.700 ± 1.761 | 103.500 ± 0.029 |
Blood glucose (Random) (mg/dL) | 129.000 ± 5.082 | 130.200 ± 4.811 | 130.800 ± 3.871 | 131.700 ± 4.666 | 130.500 ± 2.667 | 130.300 ± 2.361 |
Sodium (mmol/L) | 144.200 ± 1.225 | 144.200 ± 1.225 | 144.000 ± 1.288 | 150.400 ± 3.921 | 151.100 ± 2.074 | 151.500 ± 1.279 |
Potassium (mmol/L) | 4.478 ± 0.359 | 4.400 ± 0.200 | 4.436 ± 0.281 | 4.890 ± 0.115 | 4.940 ± 0.054 | 4.950 ± 0.093 |