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Table 4 Classification of COVID-19-associated rhino-orbital-cerebral mucormycosis (ROCM) as possible, probable and proven

From: Simplified screening and referral protocol for sinonasal mucormycosis in post COVID-19 patients

Terminology

Definition

Possible ROCM

Typical symptoms and signs of ROCM

Clinical setting of concurrent or recently treated COVID-19

Probable ROCM

Clinical features suggestive of ROCM

Supportive diagnostic nasal endoscopy findings and/or

Supportive radiological signs on contrast-enhanced magnetic resonance imaging or computed tomography scan

Proven ROCM

Clinico-radiological features suggestive of ROCM

Microbiological confirmation on direct microscopy and/or culture and/ or histopathology with special stains and/or

Molecular diagnostics

  1. (Modified from Honavar SG. Code Mucor: Guidelines for the Diagnosis, Staging and Management of Rhino-Orbito-Cerebral Mucormycosis in the Setting of COVID-19. Indian Journal of Ophthalmology. 2021;69:1361–5.) (Sen et al. 2021 Feb)